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The Jynneos monkeypox vaccine is highly effective, but two doses are needed for optimal protection.
TDF/FTC is effective for cisgender women who take at least four pills per week, but many struggle to reach this level of adherence.
An islatravir implant could potentially prevent HIV for several years, while an antiretroviral insert could offer on-demand protection.
Some people found thigh injections less painful than butt shots, and this could potentially enable self-administration at home.
Black gay men and transgender women were more likely to maintain good adherence with every-other-month shots versus daily pills.
Researchers are exploring novel strategies to help the immune system produce broadly neutralizing antibodies.
Starting HIV treatment later and having a lower CD4 count were also linked to serious non-AIDS events.
Doxycycline after sex reduces the risk of gonorrhea, chlamydia and syphilis for gay men, and it does not appear to drive resistance.
The risk of mother-to-child transmission is less than 1% if the woman is on treatment with an undetectable viral load.
Cutting the duration of treatment also cut the likelihood of a cure.
Several mechanisms may play a role, including persistent virus and ongoing immune dysregulation.
More than a quarter of HIV-positive people with a CD4 count below 100 died from mpox complications.
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