#antiretrovirals

Marc Franke is part of an exclusive circle of people cured of HIV after a stem cell transplant to treat cancer.

Gene therapy that alters CCR5 receptors and excises HIV from infected cells eliminated the virus in mice.

The risk of mother-to-child HIV transmission fell below 1% for the first time in 2019.

Individuals who maintained a low viral load without treatment had a higher rate of non-AIDS-defining conditions.

Poor sleep quality, sleep apnea and daytime sleepiness were linked to mood disorders and cardiovascular risk, but not to antiretrovirals.

Most people who died of monkeypox in the United States had advanced HIV with a CD4 count below 50.

Some people found thigh injections less painful than butt shots, and this could potentially enable self-administration at home.

Starting HIV treatment later and having a lower CD4 count were also linked to serious non-AIDS events.

The risk of mother-to-child transmission is less than 1% if the woman is on treatment with an undetectable viral load.

Women—especially Black women—are underrepresented in late-stage studies of new HIV therapies.

Gender and racial disparities in mortality persist, but the gap appears to have closed when it comes to getting the latest HIV treatment.

People with HIV who recently used marijuana were twice as likely to miss taking their meds.

Switching from TAF to TDF may help people lose weight, but this must be balanced against the risk of kidney problems and bone loss.

People with suppressed HIV respond well to mRNA vaccines, but individuals with a low CD4 count may not be adequately protected.

EBT-101 is novel gene-editing therapy that uses “molecular scissors” to cut HIV out of cells.

The updated guidance says antiretroviral therapy should be started as soon as possible after diagnosis and outlines the latest options.