Driving while depressed on antidepressants can lead to recklessness warn researchers from the University of North Dakota in Grand Forks. A recent study looked at 60 depressed participants comprised of 30 people taking at least one type of antidepressant and the other half taking no medication Researchers gave the participants computerized driving tests—braking, steering, scanning sightlines and reacting to people and other cars—and found that those who were highly depressed had worse scores on some driving skills than those who were not taking antidepressants.

“We already know that depression causes concentration problems,” says study author Holly J. Dannewitz. “And now it appears that people taking antidepressants who also have relatively higher depression scores fare significantly worse when attempting to perform a computerized simulation of driving.”